Since the outbreak of SARS-CoV-2, antigenicity concerns continue to linger with emerging mutants.As recent variants have shown decreased reactivity to previously determined monoclonal antibodies (mAbs) or sera, monitoring the antigenicity change of circulating mutants is urgently needed for vaccine effectiveness.Currently, antigenic comparison is m
Multidrug-resistant tuberculosis (MDR-TB) is on the rise, and is difficult to treat.The approval of two new drugs, bedaquiline and delamanid, and growing evidence for the use of linezolid, offer renewed hope for addressing MDR-TB.However, access to these medicines Ski de fond - Femme - Bottes - Classic remains a significant challenge.These drugs ha
Osteoporosis (OP), is a systemic bone disorder associated with low bone mass and bone tissue corrosion.Worsening of the disease condition leads to bone delicacy and fracture.Various drugs are available for the treatment of OP, however they have limitations including poor solubility, bioavailability and toxicity.Herein, Raloxifene-loaded polymeric n
In this research work, modeling and multi-objective optimization of dry foundry sand parameters were done using artificial neural network (ANN) and genetic algorithm (GA).ANN was used to predict dry compressive strength and unit production cost of dry foundry sand.The input parameters of the ANN were baking temperature, percentage additive (groundn